SPRI® (Solid Phase Reversible Immobilization) is a patented, high performance paramagnetic bead-based technology based on the selective immobilization of nucleic acids onto magnetic microparticles (Hawkins, et. al., Nucleic Acids Res. 1995 (23): 4742-4743). Agencourt offers nucleic acid isolation systems to purify DNA and RNA from samples such as cultured cells, whole blood, human cheek cells, plant material, viral particles, fresh, frozen or fixed-formalin, paraffin-embedded (FFPE) tissue, and PCR fragments. The SPRI technology allows for easy automation of nucleic acid purification with superior performance. Since its debut in 1995, the technology has been adopted by many of the largest genome research facilities around the world.



Genomic DNA Purification Kits
Agencourt DNAdvance Kits
  • Nucleic Acid Isolation from Mammalian Tissue Samples
Agencourt Genfind v2 kits
  • Genomic DNA Isolation from Blood
Agencourt Orapure Kits
  • Buccal Cell DNA Isolation
Sequencing Clean Up Kits
Agencourt CleanSEQ Kits
  • Dye Terminator Removal
PCR Reaction Products Clean Up Kits
Plasmid Purification Kits
Agencourt CosMCPrep Kits
  • High/Low Copy Fosmid and BAC Purification
RNA Purification And Clean Up Kits
Agencourt FormaPure Kits
  • Nucleic Acid Extraction from FFPE Tissues
Agencourt RNAClean Kits
Agencourt RNAClean XP Kits
  • Post-cDNA Purification and post-IVT cRNA Purification
Agencourt RNAdvance Blood Kits
  • RNA from PAXgene-Preserved Blood
Agencourt RNAdvance Cell v2 Kits
  • RNA Isolation and Purification from Cultured Eukaryotic Cells
Agencourt RNAdvance Tissue Kits
  • RNA Extraction from Tissue
Accessories
Agencourt Software
  • Automation Methods


High Quality Nucleic Acid Purifications
The Agencourt SPRI technology provides fast, high quality isolation of a wide array of nucleic acid moieties, including:
  • Plasmids
  • PCR amplicons
  • Sequencing extension products
  • BACs, fosmids, or cosmids
  • Genomic DNA
  • RNA

Simple, Automation-Friendly Purification
  • Simple, three step protocol
  • No centrifugation or filtration steps
  • No chaotropic salts or caustic materials

The tables below illustrate the compatibility of our current reagent offerings on Beckman Coulter automation.

For a PDF of the reagent automation tables CLICK HERE

nucleic

reagents


View an animated version of the Agencourt SPRI process here.